From my research it looks like Karpen Bros. was in business until 1953. The Karpen we all know and love typically dates from the 1880s through 1910 or so. If this is Karpen it is definitely later, ca. 1920s at least. The incised ornament in the styles would be consistent with that. Although the bookmatched burl is definitely conservative, the simplified nature of the other ornament would fit with a 1920s and later date.
So if the Karpen lable has never been moved, and the family operated out of Chicago (and other cities at a later date, as indicated by the label) then this is definitely American, albeit from a family of Prussian/Polish immigrants that came to the U.S. in the late 19th century.