Welcome to the forum , emconn22 .
In my experience(s) with more than 1k oil paintings I've purchased , not one was adversely affected in value by cleaning (those that were 'properly' cleaned , that is) ... matter of fact , it usually brings out hidden details that were concealed by 'soiling' on the painting .
Framing elements (wood,etc.) can be harmful to your painting , and I'd suggest you use some "acid-free" products to protect your canvas from them (there's some 'tapes' that are used to line the interior of wood frames) .
Other concerns could be those of molds/fungus in/on the canvas (often can be seen on the back of the canvas) .
The fact that you've mentioned the existence of a hole in the painting reflects , to me , a specific area that could be damaged by cleaning , however .
I'm not advocating that you get out some cleaning supplies & 'do-it-yourself' , though .
Cleaning oil paintings can be a very delicate process , depending on the condition of any given painting & all of the elements of the canvas & stretchers & such .
Nice little oil painting , emconn22 .
